Butylimidazole → HCID 178448559, compound

HRID 65240

Reaction equation

HRID 65240 reaction equation
[CH2:1]([N:5]1[CH:9]=[CH:8][N:7]=[CH:6]1)[CH2:2][CH2:3][CH3:4].[Br:10][CH2:11][CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1>>[Br-:10].[CH2:1]([N+:5]1[CH:9]=[CH:8][N:7]([CH2:11][CH2:12][CH2:13][C:14]2[CH:15]=[CH:16][C:17]([O:20][CH3:21])=[CH:18][CH:19]=2)[CH:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 61347ButylimidazoleHCID 127769961-(3-Bromopropyl)-4-methoxybenzene

Product 1

HCID 178448559HCID 178448559, compound

Conditions

Temperature
140 °C

Procedure

A mixture of 2.5 g (0.02 mole) of 1-butyl-1H-imidazole and 4.61 g (0.02 mole) of 1-(3-bromopropyl)-4-methoxybenzene is heated at 140° C. for about 1.5 hours. Follow the progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5). At the completion of the reaction, the cooled reaction product is triturated thoroughly with ether and on drying, provides the title compound.

Workup

  1. customthe progress of the reaction by thin-layer chromatography on silica gel (methanol: 1M sodium chloride, 95:5)
  2. customAt the completion of the reaction
  3. customthe cooled reaction product
  4. customis triturated thoroughly with ether
  5. customon drying

Sources & evidence

ORD record
ord-d17fe45ddae24492a2764b6e70704cee
Source dataset
uspto-grants-1986_09
Patent number
US04613609

Linked notes

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