Sodium Hypochlorite → Sodium 3,3-dimethyl-2-oxobutyrate

HRID 65490

Reaction equation

HRID 65490 reaction equation
[CH3:1][C:2]([CH3:9])([CH3:8])[CH:3]([OH:7])[C:4]([O-:6])=[O:5].[Na+:10].Cl[O-].[Na+]>O.[Ru](=O)=O.O>[CH3:1][C:2]([CH3:9])([CH3:8])[C:3](=[O:7])[C:4]([O-:6])=[O:5].[Na+:10]

Participants

5

Reactant 2

HCID 23665760Sodium HypochloriteHCID 23694960Sodium 3,3-dimethyl-2-hydroxybutyrate

Product 1

HCID 23674764Sodium 3,3-dimethyl-2-oxobutyrate

Reagents, catalysts & solvents 2

HCID 16211523Ruthenium dioxide hydrateCatalystHCID 962WaterSolvent

Procedure

Sodium 3,3-dimethyl-2-hydroxybutyrate and ruthenium dioxide hydrate are added to water, the pH rendered alkaline, and sodium hypochlorite is slowly added to produce sodium 3,3-dimethyl-2-oxobutyrate in high yield and purity. The solid catalyst is filtered off and may be re-used while the filtrate can be directly used in further synthesis.

Workup

  1. additionis slowly added

Sources & evidence

ORD record
ord-0abcb0c150bc4175a08041240e6ed897
Source dataset
uspto-grants-1986_09
Patent number
US04614822

Linked notes

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