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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 65527Generated: October 27, 2026

6-Chloropicolinic acid → 6-chloropyridine-2-carbonyl Chloride

https://huagongshe.com/reaction/65527

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloropicolinic acidHCID 20812—
ReactantThionyl ChlorideHCID 24386—
Product6-chloropyridine-2-carbonyl ChlorideHCID 10942976—

Reaction Steps

A mixture of 40 g 6-chloro-2-pyridinecarboxilic acid and 150 ml SOCl2 is refluxed 4 hrs. After removing excess SOCl2 there is obtained 44 g 6-chloro-2-pyridinecarboxylic acid chloride, m.p. 76° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04614833
Source datasetuspto-grants-1986_09
ORD IDord-729d01841d334557ae99ddc3e7803453
Source noteuspto-grants-1986_09