2,3-Dimethylquinoxaline → 3-Methylquinoxaline-2-carbaldehyde

Reaction equation

[CH3:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[Se](=O)=[O:14]>>[CH3:1][C:2]1[C:11]([CH:12]=[O:14])=[N:10][C:9]2[C:4]([N:3]=1)=[CH:5][CH:6]=[CH:7][CH:8]=2

Participants

Reactant 2

HCID 169252,3-Dimethylquinoxaline

HCID 24007Selenium Dioxide

Product 1

HCID 5888003-Methylquinoxaline-2-carbaldehydeYield 66%

Procedure

The title compound was prepared from 2,3-dimethylquinoxaline (6c) and selenium dioxide using methods as described in the literature for similar compounds (Kepez et al., 1989) in 66% yield.

Sources & evidence

ORD record: ord-92ef9f2e3368487288ec1413879569a7
Source dataset: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08071620B2

Reaction notes

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