Selenium Dioxide → 6-Methoxyquinoline-2-carbaldehyde

HRID 655887

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[C:8]([CH3:13])[CH:7]=[CH:6]2.[Se](=O)=[O:15]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[C:8]([CH:13]=[O:15])[CH:7]=[CH:6]2

Participants

Reactant 2

HCID 24007Selenium Dioxide

HCID 706486-Methoxyquinaldine

Product 1

HCID 15488726-Methoxyquinoline-2-carbaldehydeYield 68%

Procedure

The title compound was prepared from 6-methoxy-2-methylquinoline (6g) and selenium dioxide using methods as described in the literature for similar compounds (Mathes et al., 1957) in 68% yield.

Sources & evidence

ORD record: ord-047a7fe1d4444f32ad5977c87bb2f833
Source dataset: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08071620B2

Linked notes

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