Lithium Hydroxide → Dilithium monocopper(II) citrate

HRID 65823

Reaction equation

HRID 65823 reaction equation
[C:1]([O-:13])(=[O:12])[CH2:2][C:3]([CH2:8][C:9]([O-:11])=[O:10])([C:5]([O-:7])=[O:6])[OH:4].[Li+:14].[Li+].[Li+].[OH-].[Li+].[Cu:19].C([O-])(=O)CC(CC([O-])=O)(C([O-])=O)O>O>[C:1]([O-:13])(=[O:12])[CH2:2][C:3]([CH2:8][C:9]([O-:11])=[O:10])([C:5]([O-:7])=[O:6])[OH:4].[Cu+2:19].[Li+:14].[Li+:14]

Participants

6

Reactant 4

HCID 3939Lithium HydroxideHCID 13520Lithium CitrateHCID 23978CopperHCID 31348Citrate

Product 1

HCID 23056454Dilithium monocopper(II) citrate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

10 millimoles of lithium citrate were dissolved in 10 milliliters of water. To this solution, 10 millimoles of cupric chloride (CuCl2.2H2O) were added gradually with stirring. A deep blue solution was formed. This was neutralized to a pH of about 7 with 10 millimoles of lithium hydroxide (LiOH.H2O). This solution, when evaporated to dryness, gave a deep blue, semicrystalline solid. This solid was ground to a fine powder and the lithium chloride was extracted with 50 milliliters of dry methanol, five times, at 35° C. The blue solid which remained behind was evacuated to remove methanol and desiccated. An attempt was made to crystallize the salt from water-organic solvent systems, but apparently due to the extremely hygroscopic nature of the salt and the high negative charge on the ionized molecule, the solid obtained was microcrystalline to amorphous. The following formula is proposed for the 1:1 complex of copper and citrate based on elucidation of the structure and analyses described hereinafter.

Workup

  1. customA deep blue solution was formed
  2. customThis solution, when evaporated to dryness
  3. customgave a deep blue, semicrystalline solid
  4. extractionthe lithium chloride was extracted with 50 milliliters of dry methanol, five times, at 35° C
  5. custombehind was evacuated
  6. customto remove methanol
  7. customto crystallize the salt from water-organic solvent systems
  8. additionapparently due to the extremely hygroscopic nature of the salt and the high negative charge on the ionized molecule
  9. customthe solid obtained

Sources & evidence

ORD record
ord-4f353ea2a7a64395b4c6d4bfd0269ea2
Source dataset
uspto-grants-1978_12
Patent number
US04129509

Linked notes

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