Chloroacetic Acid → Ethanone, 2-chloro-1-(2,3,4-trihydroxyphenyl)-

HRID 65847

Reaction equation

[C:1]1([CH:9]=[CH:8][CH:7]=[C:5]([OH:6])[C:3]=1[OH:4])[OH:2].[Cl:10][CH2:11][C:12](O)=[O:13].P(Cl)(Cl)(Cl)=O>>[CH:8]1[C:9]([C:12]([CH2:11][Cl:10])=[O:13])=[C:1]([OH:2])[C:3]([OH:4])=[C:5]([OH:6])[CH:7]=1

Participants

Reactant 3

HCID 300Chloroacetic Acid

HCID 1057Pyrogallol

HCID 24813Phosphorus oxychloride

Product 1

HCID 87066Ethanone, 2-chloro-1-(2,3,4-trihydroxyphenyl)-

Procedure

Pyrogallol is reacted with chloracetic acid in the presence of phosphorus oxychloride to form ω-chloro-2,3,4-trihydroxyacetophenone,

Sources & evidence

ORD record: ord-a7631675cec241a8806dc99d9cfe3ee4
Source dataset: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04129575

Linked notes

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