4-Oxobutanoic acid → 1-Piperidinium

HRID 66157

Reaction equation

HRID 66157 reaction equation
[O:1]=[CH:2][CH2:3][CH2:4][C:5]([OH:7])=[O:6].[NH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>C1C=CC=CC=1>[NH2+:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1.[O:1]=[CH:2][CH2:3][CH2:4][C:5]([O-:7])=[O:6]

Participants

5

Reactant 2

HCID 11124-Oxobutanoic acidHCID 8082Piperidine

Product 2

HCID 6379691-PiperidiniumHCID 95432384-Oxobutanoate

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

100 Mg. of 4-(8-methoxy-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acid in 10 ml. of benzene is treated with 60 mg. of piperidine. The solution obtained is allowed to stand for one hour and the crystalline material which forms is filtered, washed with ether and air dried to yield piperidinium 4-(8-methoxy-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyrate.

Workup

  1. customThe solution obtained
  2. filtrationthe crystalline material which forms is filtered
  3. washwashed with ether and air
  4. customdried

Sources & evidence

ORD record
ord-95cdf6991778486985518cab3455bb88
Source dataset
uspto-grants-1978_12
Patent number
US04130654

Linked notes

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