1,1-Dichloroethane → 7-{4-[4-(6-Ethyl-pyridin-2-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one

HRID 664299

Reaction equation

HRID 664299 reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][cH:6][c:7]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[n:8]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[Cl:39][CH:40]([Cl:41])[CH3:42].[O:22]=[C:23]1[CH2:24][CH2:25][c:26]2[cH:27][cH:28][c:29]([O:33][CH2:34][CH2:35][CH2:36][CH:37]=[O:38])[n:30][c:31]2[NH:32]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][cH:5][cH:6][c:7]([N:9]2[CH2:10][CH2:11][N:12]([CH2:37][CH2:36][CH2:35][CH2:34][O:33][c:29]3[cH:28][cH:27][c:26]4[c:31]([n:30]3)[NH:32][C:23](=[O:22])[CH2:24][CH2:25]4)[CH2:13][CH2:14]2)[n:8]1

Participants

5

Reactant 4

HCID 63651,1-DichloroethaneHCID 8471TriethylamineHCID 210731761-(6-Ethylpyridin-2-YL)piperazineHCID 210733774-((7-Oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)oxy)butanal

Product 1

HCID 210737297-{4-[4-(6-Ethyl-pyridin-2-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Sources & evidence

ORD record
ord-317ac15616884d1684bc908067fbcf35
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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