Dimethyl Sulfoxide → 1-Boc-pyrrolidine-3-acetic acid

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:13]([C:14](=[O:15])[OH:16])[C:17]([OH:18])=[O:19])[CH2:11][CH2:12]1.[C:31]([O:32][CH3:33])([CH3:34])([CH3:35])[CH3:36].[CH3:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1.[CH3:27][S:28]([CH3:29])=[O:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:13][C:14](=[O:15])[OH:16])[CH2:11][CH2:12]1

Participants

Reactant 4

HCID 679Dimethyl Sulfoxide

HCID 1140Toluene

HCID 15413tert-Butyl methyl ether

HCID 666606982-(1-(Tert-butoxycarbonyl)pyrrolidin-3-yl)malonic acid

Product 1

HCID 43437711-Boc-pyrrolidine-3-acetic acid

Sources & evidence

ORD record: ord-320b2b0bfd9d40e4b152bc1e46adf2bd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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