Acetic Acid → 3-(5-Chloro-3-fluoropyridin-2-yl)-2-methyl-3-oxopropionic acid

HRID 668347

Reaction equation

HRID 668347 reaction equation
[BrH:20].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([C:8](=[O:9])[c:10]1[n:11][cH:12][c:13]([Cl:17])[cH:14][c:15]1[F:16])[CH3:18])=[O:19].[CH3:21][C:22](=[O:23])[OH:24]>>[O:5]=[C:6]([CH:7]([C:8](=[O:9])[c:10]1[n:11][cH:12][c:13]([Cl:17])[cH:14][c:15]1[F:16])[CH3:18])[OH:19]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 220135773-(5-Chloro-3-fluoropyridin-2-yl)-2-methyl-3-oxopropionic acid tert-butyl ester

Product 1

HCID 217121243-(5-Chloro-3-fluoropyridin-2-yl)-2-methyl-3-oxopropionic acid

Sources & evidence

ORD record
ord-81c238b54f8e4de998a21121fe00d4ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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