Hydrochloric Acid → 4-(2-aminopyrimidin-5-yl)-N-[4-(diethylamino)-2-methylphenyl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

HRID 668473

Reaction equation

HRID 668473 reaction equation
[CH2:55]([CH3:56])[N:57]([c:58]1[cH:59][c:60]([CH3:107])[c:61]([NH:64][C:65](=[O:66])[N:67]2[CH2:68][CH2:69][c:70]3[c:71]2[n:72][c:73]([N:101]2[CH2:102][CH2:103][O:104][CH2:105][CH2:106]2)[n:74][c:75]3-[c:76]2[cH:77][n:78][c:79]([N:82]([CH2:83][c:84]3[cH:85][cH:86][c:87]([O:88][CH3:89])[cH:90][cH:91]3)[CH2:92][c:93]3[cH:94][cH:95][c:96]([O:97][CH3:98])[cH:99][cH:100]3)[n:80][cH:81]2)[cH:62][cH:63]1)[CH2:108][CH3:109].[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[c:18]2[n:19][cH:20][c:21](-[c:22]3[c:23]4[c:27]([n:28][c:29]([N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[n:36]3)[NH:26][CH2:25][CH2:24]4)[cH:37][n:38]2)[cH:39][cH:40]1.[ClH:41].[NH2:42][c:43]1[cH:44][cH:45][c:46]([N:47]([CH2:48][CH3:49])[CH2:50][CH3:51])[cH:52][c:53]1[CH3:54]>>[CH2:55]([CH3:56])[N:57]([c:58]1[cH:59][c:60]([CH3:107])[c:61]([NH:64][C:65](=[O:66])[N:67]2[CH2:68][CH2:69][c:70]3[c:71]2[n:72][c:73]([N:101]2[CH2:102][CH2:103][O:104][CH2:105][CH2:106]2)[n:74][c:75]3-[c:76]2[cH:77][n:78][c:79]([NH2:82])[n:80][cH:81]2)[cH:62][cH:63]1)[CH2:108][CH3:109]

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 673642-Amino-5-(diethylamino)tolueneHCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amineHCID 1405471404-[2-[bis[(4-methoxyphenyl)methyl]amino]pyrimidin-5-yl]-N-[4-(diethylamino)-2-methylphenyl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

Product 1

HCID 592446754-(2-aminopyrimidin-5-yl)-N-[4-(diethylamino)-2-methylphenyl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

Sources & evidence

ORD record
ord-27a2eee90f014231b08d6974058ba1b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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