Hydrogen Peroxide → 1,2-Epoxycyclooctane
Reaction equation
OO.Cl[CH2:4][C:5]([C:7](Cl)(Cl)Cl)=[O:6].[CH:11]1[CH2:18][CH2:17]CCC[CH2:13][CH:12]=1.C(Cl)(Cl)Cl>O>[CH:4]12[O:6][CH:5]1[CH2:7][CH2:13][CH2:12][CH2:11][CH2:18][CH2:17]2Participants
6
Reactant 4
Product 1
Reagents, catalysts & solvents 1
Procedure
There were added 13.68 parts of a 50% aqueous hydrogen peroxide to a refluxing mixture of 3.92 parts of tetrachloroacetone, 11.58 parts of cyclooctene and 149 parts of chloroform. Water was removed continuously as it was formed, over a period of 4 hours of heating. The removed water was then added to the reaction mixture. The organic phase was then separated from the aqueous phase. Based on VPC analysis there was obtained an 83% yield of cyclooctene oxide.
Workup
- customWater was removed continuously as it
- customwas formed, over a period of 4 hours
- temperatureof heating
- customThe organic phase was then separated from the aqueous phase
Sources & evidence
- ORD record
- ord-07e7b8d911554e5d89dde51561daed3a
- Source dataset
- uspto-grants-1982_08
- Patent number
- US04344887
Reaction notes
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