Dichloromethane → 1-[4-[6-Bromo-2-(2-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]-2-hydroxy-4-methylpentan-1-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:19])[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[Cl:41][CH2:42][Cl:43].[OH:27][CH:28]([C:29](=[O:30])[N:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1)[CH2:37][CH:38]([CH3:39])[CH3:40]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:34]3[CH2:33][CH2:32][N:31]([C:29]([CH:28]([OH:27])[CH2:37][CH:38]([CH3:39])[CH3:40])=[O:30])[CH2:36][CH2:35]3)[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1Participants
5
