2-Tolyl isocyanate → HCID 178424380, compound

HRID 67642

Reaction equation

HRID 67642 reaction equation
[OH:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH3:8])[CH:3]=1.[C:9]1([CH3:18])[C:10]([N:15]=[C:16]=[O:17])=[CH:11][CH:12]=[CH:13][CH:14]=1>C1(C)C(C)=CC=CC=1>[OH:1][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH3:8])[C:3]=1[C:16]([NH:15][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[CH3:18])=[O:17]

Participants

4

Reactant 2

HCID 691942-Tolyl isocyanateHCID 178429390HCID 178429390, compound

Product 1

HCID 178424380HCID 178424380, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

A mixture of 22.4 g (0.2 mol) 5-hydroxy-1,3-dimethyl-1H-pyrazole [K. Auwers, J.Prakt.Chem., 110, 153 (1925)], 26.6 g (0.2 mol) o-tolylisocyanate in 150 ml xylene containing 1 ml triethylamine is heated to reflux for 1.5 hours.

Workup

  1. temperatureis heated
  2. temperatureto reflux for 1.5 hours

Sources & evidence

ORD record
ord-641a77feb1c94802982b5f42d991a4be
Source dataset
uspto-grants-1982_08
Patent number
US04346097

Linked notes

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