Tetrahydrofuran → methyl 5-amino-4-[7-[(1-methylindazol-3-yl)methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

HRID 676979

Reaction equation

HRID 676979 reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:36][n:37]1[n:38][c:39]([CH2:46][OH:47])[c:40]2[cH:41][cH:42][cH:43][cH:44][c:45]12.[NH2:15][C:16]([CH:17]([CH2:18][CH2:19][C:20](=[O:21])[O:22][CH3:23])[N:24]1[C:25](=[O:34])[c:26]2[cH:27][cH:28][cH:29][c:30]([OH:33])[c:31]2[CH2:32]1)=[O:35].[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14]>>[NH2:15][C:16]([CH:17]([CH2:18][CH2:19][C:20](=[O:21])[O:22][CH3:23])[N:24]1[C:25](=[O:34])[c:26]2[cH:27][cH:28][cH:29][c:30]([O:33][CH2:46][c:39]3[n:38][n:37]([CH3:36])[c:45]4[c:40]3[cH:41][cH:42][cH:43][cH:44]4)[c:31]2[CH2:32]1)=[O:35]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 7164546(1-methyl-1H-indazol-3-yl)methanolHCID 58389139Methyl 5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate

Product 1

HCID 67335229methyl 5-amino-4-[7-[(1-methylindazol-3-yl)methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate

Sources & evidence

ORD record
ord-23af1b3f5911497ab3ee3f0ee0b9e421
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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