Acetone → 4-(N-piperidinomethylcarbonyl-N-methyl-amino)-nitrobenzene

Reaction equation

[Br:1][CH2:2][C:3](=[O:4])[N:5]([CH3:6])[c:7]1[cH:8][cH:9][c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]1.[C:16](=[O:17])([O-:18])[O-:19].[CH2:22]1[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1.[CH3:28][C:29](=[O:30])[CH3:31].[K+:20].[K+:21]>>[CH2:2]([C:3](=[O:4])[N:5]([CH3:6])[c:7]1[cH:8][cH:9][c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]1)[N:25]1[CH2:24][CH2:23][CH2:22][CH2:27][CH2:26]1

Participants

Reactant 5

HCID 180Acetone

HCID 813Potassium Cation2×

HCID 8082Piperidine

HCID 19660Carbonate Ion

HCID 226683752-bromo-N-methyl-N-(4-nitrophenyl)acetamide

Product 1

HCID 235071034-(N-piperidinomethylcarbonyl-N-methyl-amino)-nitrobenzene

Sources & evidence

ORD record: ord-9ccaf7edbd00407f9626f07f85c99708
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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