2-Bromopropane → 2-[1-(3,4-dimethoxy-benzyl)-5-isopropoxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

Reaction equation

[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:20][C:21](=[O:22])[NH:23][CH2:24][c:25]3[n:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:9][CH2:10][c:11]3[c:12]([OH:19])[cH:13][cH:14][c:15]([O:17][CH3:18])[c:16]32)[cH:31][cH:32][c:33]1[O:34][CH3:35].[CH:36]([CH3:37])([CH3:38])[Br:39]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][CH:7]2[N:8]([CH2:20][C:21](=[O:22])[NH:23][CH2:24][c:25]3[n:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:9][CH2:10][c:11]3[c:12]([O:19][CH:36]([CH3:37])[CH3:38])[cH:13][cH:14][c:15]([O:17][CH3:18])[c:16]32)[cH:31][cH:32][c:33]1[O:34][CH3:35]

Participants

Reactant 2

HCID 63582-Bromopropane

HCID 227425532-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

Product 1

HCID 227425292-[1-(3,4-dimethoxy-benzyl)-5-isopropoxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

Sources & evidence

ORD record: ord-60b250ea301743a8af468e6ee576c008
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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