Dichloromethane → 2-Bromo-5-methoxy-3-methyl-phenylamine

Reaction equation

[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([Br:17])[c:10]([CH3:16])[cH:11][c:12]([O:14][CH3:15])[cH:13]1)([CH3:5])([CH3:6])[CH3:18].[Cl:26][CH2:27][Cl:28].[OH:19][C:20]([C:21]([F:22])([F:23])[F:24])=[O:25]>>[NH2:7][c:8]1[c:9]([Br:17])[c:10]([CH3:16])[cH:11][c:12]([O:14][CH3:15])[cH:13]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 69586528(2-Bromo-5-methoxy-3-methyl-phenyl)-carbamic acid tert-butyl ester

Product 1

HCID 218864892-Bromo-5-methoxy-3-methyl-phenylamine

Sources & evidence

ORD record: ord-a3c9c60e30fb4bfa8562796be53b38e8
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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