5-Amino-2-methylpyridine → N(8)-(3-Methoxy-benzyl)-N(2)-(6-methyl-pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

Reaction equation

[CH3:21][c:22]1[cH:23][cH:24][c:25]([NH2:28])[cH:26][n:27]1.[Cl:1][c:2]1[n:3][n:4]2[c:5]([c:6]([NH:10][CH2:11][c:12]3[cH:13][c:14]([O:18][CH3:19])[cH:15][cH:16][cH:17]3)[cH:7][cH:8][cH:9]2)[n:20]1>>[c:2]1([NH:28][c:25]2[cH:24][cH:23][c:22]([CH3:21])[n:27][cH:26]2)[n:3][n:4]2[c:5]([c:6]([NH:10][CH2:11][c:12]3[cH:13][c:14]([O:18][CH3:19])[cH:15][cH:16][cH:17]3)[cH:7][cH:8][cH:9]2)[n:20]1

Participants

Reactant 2

HCID 2433135-Amino-2-methylpyridine

HCID 67481427(2-Chloro-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-(3-methoxy-benzyl)-amine

Product 1

HCID 59612599N(8)-(3-Methoxy-benzyl)-N(2)-(6-methyl-pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

Sources & evidence

ORD record: ord-7eca46a837134ebb992baed125508664
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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