Potassium Cation → 3-[2,4-Dichloro-5-(propargyloxy)phenyl]-1-methyl-6-trifluoromethyl-2-oxo-1,2-dihydropyrazine

Reaction equation

[C:22](=[O:23])([O-:24])[O-:25].[CH2:28]([C:29]#[CH:30])[Br:31].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[c:3](-[c:10]2[c:11](=[O:21])[n:12]([CH3:20])[c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][n:15]2)[cH:4][c:5]([OH:9])[c:6]([Cl:8])[cH:7]1.[K+:26].[K+:27].[OH2:32]>>[Cl:1][c:2]1[c:3](-[c:10]2[c:11](=[O:21])[n:12]([CH3:20])[c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][n:15]2)[cH:4][c:5]([O:9][CH2:30][C:29]#[CH:28])[c:6]([Cl:8])[cH:7]1

Participants

Reactant 6

HCID 813Potassium Cation2×

HCID 962Water

HCID 6228Dimethylformamide

HCID 7842Propargyl bromide

HCID 19660Carbonate Ion

HCID 193655303-(2,4-Dichloro-5-hydroxyphenyl)-1-methyl-6-trifluoromethyl-2-oxo-1,2-dihydropyrazine

Product 1

Sources & evidence

ORD record: ord-2a4e55b235364cfab84c26509ae01a52
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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