Sodium ion → Propan-2-yl 4-[[7-(4-bromophenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylate

HRID 685958Notes

Reaction equation

HRID 685958 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][c:11]3[c:12]2[n:13][cH:14][n:15][c:16]3[Cl:17])[cH:6][cH:7]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[H-:32].[Na+:31].[OH:18][CH:19]1[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][CH:28]([CH3:29])[CH3:30])[CH2:23][CH2:24]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][c:11]3[c:12]2[n:13][cH:14][n:15][c:16]3[O:18][CH:19]2[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][CH:28]([CH3:29])[CH3:30])[CH2:23][CH2:24]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 16745126Isopropyl 4-Hydroxypiperidine-1-carboxylateHCID 866374027-(4-Bromophenyl)-4-chloro-5,6-dihydropyrrolo[2,3-d]pyrimidine

Product 1

HCID 69062843Propan-2-yl 4-[[7-(4-bromophenyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-4-yl]oxy]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-ef4c7ff6dd414fd098787450255eb51b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…