Acetic Acid → 1-(3-Amino-4,6-difluorophenyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

HRID 685964

Reaction equation

HRID 685964 reaction equation
[C:28]([OH:29])(=[O:30])[CH3:31].[ClH:32].[NH2:1][c:2]1[cH:3][c:4](-[n:10]2[cH:11][c:12]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[c:13](=[O:22])[c:14]3[cH:15][c:16]([F:21])[c:17]([Cl:20])[n:18][c:19]23)[c:5]([F:9])[cH:6][c:7]1[F:8].[OH2:33]>>[NH2:1][c:2]1[cH:3][c:4](-[n:10]2[cH:11][c:12]([C:23](=[O:24])[OH:25])[c:13](=[O:22])[c:14]3[cH:15][c:16]([F:21])[c:17]([Cl:20])[n:18][c:19]23)[c:5]([F:9])[cH:6][c:7]1[F:8]

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 962WaterHCID 53833255Ethyl 1-(3-amino-4,6-difluorophenyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate

Product 1

HCID 110899701-(3-Amino-4,6-difluorophenyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-2188de5bff5245bcae9d09bfba67e984
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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