Hydrochloric Acid → 6-(3,4-Dimethoxy-phenyl)-4-(1,3-dimethyl-1H-pyrazol-4-ylamino)-[1,5]naphthyridine-3-carboxylic acid ethyl ester

HRID 688287

Reaction equation

HRID 688287 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8][c:9]2[cH:10][cH:11][c:12](-[c:17]3[cH:18][c:19]([O:25][CH3:26])[c:20]([O:23][CH3:24])[cH:21][cH:22]3)[n:13][c:14]2[c:15]1[Cl:16].[CH3:27][n:28]1[n:29][c:30]([CH3:34])[c:31]([NH2:33])[cH:32]1.[CH3:36][N:37]1[C:38]([CH3:39])([CH3:40])[CH2:41][CH2:42][CH2:43][C:44]1([CH3:45])[CH3:46].[ClH:35]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8][c:9]2[cH:10][cH:11][c:12](-[c:17]3[cH:18][c:19]([O:25][CH3:26])[c:20]([O:23][CH3:24])[cH:21][cH:22]3)[n:13][c:14]2[c:15]1[NH:33][c:31]1[c:30]([CH3:34])[n:29][n:28]([CH3:27])[cH:32]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6603PempidineHCID 44310561,3-dimethyl-1H-pyrazol-4-amineHCID 596197304-Chloro-6-(3,4-dimethoxy-phenyl)-[1,5]naphthyridine-3-carboxylic acid ethyl ester

Product 1

HCID 596198526-(3,4-Dimethoxy-phenyl)-4-(1,3-dimethyl-1H-pyrazol-4-ylamino)-[1,5]naphthyridine-3-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-e965516b713d4f31bc479c14cecf3f62
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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