Dimethylacetamide → N-{2-Chloro-6-[1-(3-ethoxy-4-methoxy-benzyl)-piperidin-4-ylamino]-pyrimidin-4-yl}-acetamide

HRID 689100

Reaction equation

HRID 689100 reaction equation
[CH2:13]([CH3:14])[O:15][c:16]1[cH:17][c:18]([CH2:19][N:20]2[CH2:21][CH2:22][CH:23]([NH2:26])[CH2:24][CH2:25]2)[cH:27][cH:28][c:29]1[O:30][CH3:31].[CH3:32][C:33]([N:34]([CH3:35])[CH3:36])=[O:37].[Cl:1][c:2]1[n:3][c:4]([Cl:12])[cH:5][c:6]([NH:8][C:9]([CH3:10])=[O:11])[n:7]1>>[Cl:1][c:2]1[n:3][c:4]([NH:26][CH:23]2[CH2:22][CH2:21][N:20]([CH2:19][c:18]3[cH:17][c:16]([O:15][CH2:13][CH3:14])[c:29]([O:30][CH3:31])[cH:28][cH:27]3)[CH2:25][CH2:24]2)[cH:5][c:6]([NH:8][C:9]([CH3:10])=[O:11])[n:7]1

Participants

4

Reactant 3

HCID 31374DimethylacetamideHCID 4713752N-(2,6-dichloropyrimidin-4-yl)acetamideHCID 392574451-(3-Ethoxy-4-methoxy-benzyl)-piperidin-4-ylamine

Product 1

HCID 86618534N-{2-Chloro-6-[1-(3-ethoxy-4-methoxy-benzyl)-piperidin-4-ylamino]-pyrimidin-4-yl}-acetamide

Sources & evidence

ORD record
ord-5a08acf73e494a029db6bcdafd28fe7c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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