Sodium Thiosulfate → 2-[4-(1,4-Dioxa-7-aza-spiro[4.4]non-7-yl)-3-fluorophenyl]-6-methoxy-2H-isoquinolin-1-one

Reaction equation

CC(OI1(OC(C)=O)(OC(C)=O)OC(=O)C2C=CC=CC1=2)=O.[O:23]1[C:27]2([CH2:31][CH2:30][N:29]([C:32]3[CH:37]=[CH:36][C:35]([NH:38][C:39](=[O:51])[C:40]4[CH:45]=[CH:44][C:43]([O:46][CH3:47])=[CH:42][C:41]=4[CH2:48][CH2:49]O)=[CH:34][C:33]=3[F:52])[CH2:28]2)[O:26][CH2:25][CH2:24]1.[O-]S([O-])(=S)=O.[Na+].[Na+]>C(Cl)Cl>[O:26]1[C:27]2([CH2:31][CH2:30][N:29]([C:32]3[CH:37]=[CH:36][C:35]([N:38]4[CH:49]=[CH:48][C:41]5[C:40](=[CH:45][CH:44]=[C:43]([O:46][CH3:47])[CH:42]=5)[C:39]4=[O:51])=[CH:34][C:33]=3[F:52])[CH2:28]2)[O:23][CH2:24][CH2:25]1