Bromide ion → 3-chloro-N-(2,6-difluorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-2-sulfonamide

Reaction equation

[Br-:32].[CH3:1][c:2]1[n:3][c:4]2[n:5]([c:6]([CH3:8])[cH:7]1)[n:9][c:10]([S:12](=[O:13])(=[O:14])[NH:15][c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[cH:11]2.[CH3:34][C:35]#[N:36].[Cl:24][N:25]1[C:26](=[O:27])[CH2:28][CH2:29][C:30]1=[O:31].[K+:33]>>[CH3:1][c:2]1[n:3][c:4]2[n:5]([c:6]([CH3:8])[cH:7]1)[n:9][c:10]([S:12](=[O:13])(=[O:14])[NH:15][c:16]1[c:17]([F:23])[cH:18][cH:19][cH:20][c:21]1[F:22])[c:11]2[Cl:24]

Participants

Reactant 5

HCID 259Bromide ion

HCID 813Potassium Cation

HCID 6342Acetonitrile

HCID 31398Chlorosuccinimide

HCID 157254205,7-dimethyl-N-(2,6-difluorophenyl)pyrazolo[1,5-a]pyrimidine-2-sulfonamide

Product 1

HCID 157254213-chloro-N-(2,6-difluorophenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-2-sulfonamide

Sources & evidence

ORD record: ord-fd711368547046aeac886ff91a4061f2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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