Dichloromethane → 4-Aminonicotinic acid

HRID 700911

Reaction equation

HRID 700911 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[cH:10][cH:11][n:12][cH:13][c:14]1[C:15](=[O:16])[OH:17])([CH3:5])([CH3:6])[CH3:7].[Cl:25][CH2:26][Cl:27].[F:18][C:19]([F:20])([F:21])[C:22]([OH:23])=[O:24]>>[NH2:8][c:9]1[cH:10][cH:11][n:12][cH:13][c:14]1[C:15](=[O:16])[OH:17]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 221726234-{[(Tert-butoxy)carbonyl]amino}pyridine-3-carboxylic acid

Product 1

HCID 3199794-Aminonicotinic acid

Sources & evidence

ORD record
ord-feb950ed1179440286065cb6b112f1bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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