N,N-Dimethylaniline → 4-Chloro-2-(pyridin-3-yl)-6-methylthieno[2,3-d]pyrimidine

HRID 701865

Reaction equation

HRID 701865 reaction equation
[CH3:23][N:24]([c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[CH3:31].[O:6]=[c:7]1[c:8]2[c:9]([n:10][c:11](-[c:13]3[cH:14][n:15][cH:16][cH:17][cH:18]3)[nH:12]1)[s:19][c:20]([CH3:22])[cH:21]2.[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[Cl:3][c:7]1[c:8]2[c:9]([n:10][c:11](-[c:13]3[cH:14][n:15][cH:16][cH:17][cH:18]3)[n:12]1)[s:19][c:20]([CH3:22])[cH:21]2

Participants

4

Reactant 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 232879063,4-Dihydro-4-oxo-2-(pyridin-3-yl)-6-methylthieno[2,3-d]pyrimidine

Product 1

HCID 184604134-Chloro-2-(pyridin-3-yl)-6-methylthieno[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-c166881224fd4c2cbe98dc0f4c8deb94
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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