N-methyl-2-pyrrolidone → N-(3,4-dimethoxybenzyl)-7-(2-fluorobenzyl)4-(2-furyl)-7H-pyrrolo[2,3-d]pyrimidine-2-amine

HRID 702920

Reaction equation

HRID 702920 reaction equation
[CH2:24]([c:25]1[cH:26][c:27]([O:28][CH3:29])[c:30]([O:31][CH3:32])[cH:33][cH:34]1)[NH2:35].[CH3:36][N:37]1[CH2:38][CH2:39][CH2:40][C:41]1=[O:42].[Cl:1][c:2]1[n:3][c:4](-[c:19]2[o:20][cH:21][cH:22][cH:23]2)[c:5]2[c:6]([n:7]1)[n:8]([CH2:11][c:12]1[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]1)[cH:9][cH:10]2>>[c:2]1([NH:35][CH2:24][c:25]2[cH:26][c:27]([O:28][CH3:29])[c:30]([O:31][CH3:32])[cH:33][cH:34]2)[n:3][c:4](-[c:19]2[o:20][cH:21][cH:22][cH:23]2)[c:5]2[c:6]([n:7]1)[n:8]([CH2:11][c:12]1[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]1)[cH:9][cH:10]2

Participants

4

Reactant 3

HCID 13387N-methyl-2-pyrrolidoneHCID 79832VeratrylamineHCID 219764272-chloro-7-(2-fluorobenzyl)-4-(2-furyl)-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 21976416N-(3,4-dimethoxybenzyl)-7-(2-fluorobenzyl)4-(2-furyl)-7H-pyrrolo[2,3-d]pyrimidine-2-amine

Sources & evidence

ORD record
ord-a9f48f1b0f62405c830aa925b21a91d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Linked notes

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