Selenium Dioxide → 4-Bromo-2,1,3-benzoselenadiazole
Reaction equation
[Br:1][C:2]1[C:3]([NH2:9])=[C:4]([NH2:8])[CH:5]=[CH:6][CH:7]=1.[Se:10](=O)=O>C(O)C.O>[Br:1][C:2]1[C:3]2[C:4](=[N:8][Se:10][N:9]=2)[CH:5]=[CH:6][CH:7]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
The specific preparation is described as follows: refluxing 3-bromo-1,2-diaminobenzene in ethanol solution, then adding into selenium dioxide dissolved in hot water, after that, refluxing for 2 hours. The precipitation is recrystallized with ethyl acetate after being filtered to get 4-bromo-2,1,3-benzoselenadiazole finally.
Workup
- customThe specific preparation
- temperatureafter that, refluxing for 2 hours
- customThe precipitation
- customis recrystallized with ethyl acetate
- filtrationafter being filtered
Sources & evidence
- ORD record
- ord-7150227821db4b80bc2389f71b850cfe
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08822634B2
Reaction notes
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