Butyl bromide → 2-Nitro-6-butoxybenzonitrile

Reaction equation

[OH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[C:3]=1[C:4]#[N:5].[CH2:13](Br)[CH2:14][CH2:15][CH3:16]>>[N+:10]([C:6]1[CH:7]=[CH:8][CH:9]=[C:2]([O:1][CH2:13][CH2:14][CH2:15][CH3:16])[C:3]=1[C:4]#[N:5])([O-:12])=[O:11]

Participants

Reactant 2

HCID 8002Butyl bromide

HCID 125032052-Hydroxy-6-nitrobenzonitrile

Product 1

HCID 247777802-Nitro-6-butoxybenzonitrile

Procedure

Prepared in a similar manner as Example 115c from 2-hydroxy-6-nitrobenzonitrile (Example 115d) and butyl bromide to provide 2-nitro-6-butoxybenzonitrile.

Sources & evidence

ORD record: ord-525924e201fc4947b7339299496ce24e
Source dataset: uspto-grants-2015_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09181276B2

Reaction notes

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