(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → D-Arabitol

HRID 713540

Reaction equation

HRID 713540 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9](CO)[OH:10])[OH:8])[OH:6])[OH:4]>C(O)C>[CH2:2]([OH:1])[C@@H:3]([C@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH2:9]([OH:10])[C@@H:7]([OH:8])[CH:5]([OH:6])[C@H:3]([OH:4])[CH2:2][OH:1]

Participants

4

Reactant 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 2

HCID 94154D-ArabitolHCID 178418489HCID 178418489, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The parent strain 3118 (ura+ version of 3099 prior to marker loopout) and the insertion site control strain 3862 produced 20-21 g/L ethanol in 55 hours, whereas strain 3082 produced 28 g/L in the same period (FIG. 33). In all three strains, glucose was depleted by nine hours. The additional ethanol formation in strain 3082 was correlated with an increased consumption of xylose. Strain 3082 produced less xylitol throughout the fermentation, and higher levels of glycerol and arabitol. Metabolite formation is summarized in Table 9.

Workup

  1. customwhereas strain 3082 produced 28 g/L in the same period (FIG. 33)
  2. customThe additional ethanol formation in strain 3082 was correlated with an increased consumption of xylose

Sources & evidence

ORD record
ord-2fc6c085b7cc4d6797f0b70ea192c62b
Source dataset
uspto-grants-2015_11
Patent number
US09181563B2

Linked notes

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