Reaction equation
[CH2:1]([C@:3]1([OH:28])[C:25]2[CH:24]=[C:23]3[N:10]([CH2:11][C:12]4[C:13]3=[N:14][C:15]3[CH:16]=[C:17]([F:22])[CH:18]=[CH:19][C:20]=3[CH:21]=4)[C:9](=[O:26])[C:8]=2[CH2:7][O:6][C:5](=[O:27])[CH2:4]1)[CH3:2].[CH:29]1([CH2:35][CH2:36]C=O)[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1>>[CH:29]1([CH2:35][CH2:36][C:21]2[C:20]3[CH:19]=[CH:18][C:17]([F:22])=[CH:16][C:15]=3[N:14]=[C:13]3[C:23]4[N:10]([CH2:11][C:12]=23)[C:9](=[O:26])[C:8]2[CH2:7][O:6][C:5](=[O:27])[CH2:4][C@@:3]([CH2:1][CH3:2])([OH:28])[C:25]=2[CH:24]=4)[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1Participants
3
Reactant 2
Product 1
Procedure
The product of Example 84 is treated with 3-cyclohexylpropanal according to a procedure similar to Stage 95e in order to produce the expected solid.
Workup
- customto produce the expected solid
Sources & evidence
- ORD record
- ord-28a0670951cb4d05bb768d2bf53334a3
- Source dataset
- uspto-grants-2006_11
- Patent number
- US07135478B2
Linked notes
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