1-Bromo-4-nitrobenzene → 4-Nitro-1,1'-biphenyl

HRID 72093

Reaction equation

HRID 72093 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7](Br)=[CH:6][CH:5]=1)([O-:3])=[O:2].[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 114661-Bromo-4-nitrobenzeneHCID 66827Phenylboronic Acid

Product 1

HCID 71144-Nitro-1,1'-biphenyl

Procedure

4-Nitro-bromobenzene and phenyl boronic acid were reacted as described in Example 6. The catalyst was recovered by filtration, washed and dried (as described in Example 1). This process was then repeated 4 times with fresh reagents and the recycled catalyst. The yields of isolated 4-Nitrobiphenyl were as follows:

Workup

  1. filtrationThe catalyst was recovered by filtration
  2. washwashed
  3. customdried (as described in Example 1)

Sources & evidence

ORD record
ord-05b04c0b57cb4631982c99303f558e8c
Source dataset
uspto-grants-2014_09
Patent number
US08828902B2

Linked notes

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