4-Methoxybenzoic Acid → Benzenepropanoic acid, 4-methoxy-beta-oxo-, ethyl ester

HRID 729880

Reaction equation

HRID 729880 reaction equation
O=[C:2]([C:9]1SC=[CH:12][CH:13]=1)[CH2:3][C:4]([O:6][CH2:7]C)=O.S1C=CC=C1C1C=CN=C(N)N=1.C[C:27]1([CH3:35])[O:32][C:31](=[O:33])[CH2:30][C:29](=[O:34])O1.COC1C=CC(C(O)=O)=CC=1>>[O:34]=[C:29]([C:9]1[CH:2]=[CH:3][C:4]([O:6][CH3:7])=[CH:12][CH:13]=1)[CH2:30][C:31]([O:32][CH2:27][CH3:35])=[O:33]

Participants

5

Reactant 4

HCID 74784-Methoxybenzoic AcidHCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 255159Ethyl 3-oxo-3-(thiophen-2-yl)propanoateHCID 27644074-(Thiophen-2-yl)pyrimidin-2-amine

Product 1

HCID 76150Benzenepropanoic acid, 4-methoxy-beta-oxo-, ethyl ester

Procedure

This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 4-methoxybenzoic acid.

Workup

  1. customThis material is prepared by a method analogous to

Sources & evidence

ORD record
ord-82295e10267f4ee6aeed2528534eca3e
Source dataset
uspto-grants-2009_09
Patent number
US07582645B2

Linked notes

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