2,2,3,3,3-Pentafluoropropanol → 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate

HRID 733288

Reaction equation

HRID 733288 reaction equation
FC(F)(F)S([O:6][S:7]([C:10]([F:13])([F:12])[F:11])(=[O:9])=[O:8])(=O)=O.[F:16][C:17]([F:24])([C:20]([F:23])([F:22])[F:21])[CH2:18]O>>[F:13][C:10]([F:11])([F:12])[S:7]([O:6][CH2:18][C:17]([F:24])([F:16])[C:20]([F:23])([F:22])[F:21])(=[O:8])=[O:9]

Participants

3

Reactant 2

HCID 98722,2,3,3,3-PentafluoropropanolHCID 67749Trifluoromethanesulfonic anhydride

Product 1

HCID 27760192,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonateYield 97%

Conditions

Temperature
90 °C

Procedure

A mixture of trifluoromethanesulfonic anhydride (40 mL, 0.24 mol) and 2,2,3,3,3-pentafluoropropanol (25 mL, 0.24 mol) was heated under argon at 90° C. overnight. Then, the crude mixture was distilled at atmospheric pressure to give the desired product as a colourless oil (97% yield).

Workup

  1. distillationThen, the crude mixture was distilled at atmospheric pressure

Sources & evidence

ORD record
ord-5c7fcfdc30414347a5f208e1333ccbe4
Source dataset
uspto-grants-2009_09
Patent number
US07589125B2

Linked notes

Loading…