Disodium glutamate → Zinc L-glutamate Dihydrate

HRID 733499

Reaction equation

HRID 733499 reaction equation
N[C@H](C([O-])=O)CCC([O-])=[O:6].[Sr+2].N[C@H](C([O-])=O)CCC([O-])=[O:17].[Na+].[Na+].O.[Na+].[NH2:26][C@H:27]([C:33]([O-:35])=[O:34])[CH2:28][CH2:29][C:30]([OH:32])=[O:31].[Cl-].[Zn+2:37].[Cl-]>O>[OH2:6].[OH2:17].[NH2:26][C@H:27]([C:33]([O-:35])=[O:34])[CH2:28][CH2:29][C:30]([O-:32])=[O:31].[Zn+2:37]

Participants

6

Reactant 4

HCID 167560Disodium glutamateHCID 3007855ZincchlorideHCID 11390644Strontium glutamateHCID 23666328Sodium L-glutamate hydrate

Product 1

HCID 22825209Zinc L-glutamate DihydrateYield 95%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
132 °C

Procedure

Basically the reaction conditions found for preparation of strontium L-glutamate (Example 8) was employed. A suspension of sodium glutamate (white coloured) is prepared by adding 100 mL of millipore water to 18.714 g (0.1 moles) of solid L-glutamic acid monosodium salt monohydrate (ALDRICH G2834, MW 187.14, CAS 142-47-2) in a 250 mL beaker. To this suspension was added 13.628 g (0.1 moles) of solid zinc chloride (FLUKA, 96469, MW 136.28, CAS 7646-85-7). The reactants were placed in the sealed container in an autoclave, and temperature was increased to 132° C. for 15 min whereafter the reaction was stopped and after the reaction mixture reached a temperature of 92-98° C., it was filtered on a Büchner funnel, and the desired zinc L-glutamate salt readily precipitated from the filtrate. The yield was approximately 95% and purity higher than 96%.

Workup

  1. customBasically the reaction conditions
  2. customis prepared
  3. customa temperature of 92-98° C., it
  4. filtrationwas filtered on a Büchner funnel
  5. customthe desired zinc L-glutamate salt readily precipitated from the filtrate

Sources & evidence

ORD record
ord-046363dd95f34e7b96700e2a4adbda65
Source dataset
uspto-grants-2009_09
Patent number
US07589235B2

Linked notes

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