CAS 16177-21-2 Disodium glutamate (HCID 167560)

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Basic information

CAS: 16177-21-2
Standard SMILES: N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
InChIKey: PXEDJBXQKAGXNJ-QTNFYWBSSA-L
Molecular formula: C5H7NNa2O4
Average molar mass: 191.09 g/mol
Monoisotopic mass: 191.01704626

Overview

Disodium L-glutamate is an organic sodium salt that is the disodium salt of L-glutamic acid. It contains a L-glutamate(2-).

Names & identifiers

Preferred name: Disodium glutamate
IUPAC: disodium;(2S)-2-aminopentanedioate
English name: l-Glutamic acid, N-coco acyl derivs., disodium salts
Molecular formula: C5H7NNa2O4
Molecular weight: 0

Names & synonyms

Disodium glutamateDisodium L-glutamateL-Glutamic acid, disodium saltL-Glutamic acid disodium saltdisodium (2S)-2-aminopentanedioateUNII-H0US799L9MH0US799L9MGlutamic acid, disodium salt, L-EINECS 240-733-5DISODIUM S-GLUTAMATEDISODIUM GLUTAMATE, L-CHEBI:91250

Show more names

Einecs 269-085-1Disodium Cocoyl Glutamtedisodium salts USP/EP/BP(2S)-2-aminopentanedioateDisodium N-Cocoyl glutamateDisodium N-Coco acyl-L-Glutamatel-Glutamic acid, N-coco acyl derivsSodium L-glutamate (30% aqueous solution)l-Glutamic acid, N-coco acyl derivs., disodium salts

DTXSID00894749GLUTAMIC ACID DISODIUM SALTL(+)-GLUTAMIC ACID DISODIUM SALTRefChem:135040DTXCID90132435516690-92-9Sodium L-glutamateDisodium cocoyl glutamate

Database identifiers

CAS

Properties

Computed structural properties

Topological polar surface area: 106 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 5
Rotatable bonds: 2
Heavy atoms: 12
Formal charge: 0
Complexity: 134

Experimental & physicochemical properties

CosmeticsCosmetic ingredients (Disodium Cocoyl Glutamate) -> CIR (Cosmetic Ingredient Review)

Physicochemical properties

Density: 1.318 · 1.318[at 20℃]
vapor pressure: 0 Pa · 0Pa at 20℃
pka: 1.52 · 1.52[at 20 ℃]
Water Solubility: 450 g/L · 450g/L at 20℃
Cosmetics Ingredients Functions: SURFACTANT - CLEANSINGCLEANSING
Cosmetic Ingredient Review (CIR): l-Glutamic acid, N-coco acyl derivs., disodium salts (68187-30-4)
LogP: -4.48 at · -4.48 at 20℃
EWG's Food Scores: 1 · 1
FDA UNII: 0 CP8F5A · MBK0CP8F5A
EPA Substance Registry System: L-Glutamic acid, N-coco acyl derivs., disodium salts (68187-30-4)
Signal word: Warning
Hazard statements

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 3.4% (1 of 29) of reports.

Warning

H319 (96.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 29 reports by companies from 2 notifications to the ECHA C&L Inventory.

This chemical does not meet GHS hazard criteria for 100% (25 of 25) of all reports.

Hazard information

Regulatory InformationDisodium L-glutamate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and Categories · 2 items

Eye Irrit. 2 (96.6%)

Not Classified

Toxicology

Toxicity Summary · 2 items

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Disodium Cocoyl Glutamate

Safe for use in cosmetics, with qualifications