HuagongsheHuagongshe Chemistry Print Report · For research reference only
BROMINE CHLORIDE (BrCl) → 2-(4-Bromothiophen-2-ylethynyl)-5-(4-chlorophenyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | BROMINE CHLORIDE (BrCl) | HCID 61697 | — |
| Reactant | Thiophene, 2,4-dibromo- | HCID 2724560 | — |
| Reactant | 5-(4-Chloro-phenyl)-2-ethynyl-pyridine | HCID 57845328 | — |
| Product | 2-(4-Bromothiophen-2-ylethynyl)-5-(4-chlorophenyl)pyridine | HCID 69055435 | — |
Reaction Steps
The product was obtained analogously to Example 7.1e starting from 2,4-dibromothiophene and 5-(4-chlorophenyl)-2-ethynylpyridine. Yield: 0.78 g (50% of theoretical); C17H9BrClNS (M=374.683); calc.: molpeak (M+H)+: 374/376/378 (BrCl); found: molpeak (M+H)+: 374/376/378 (BrCl); HPLC-MS: 7.40 minutes (method B).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07592358B2 |
| Source dataset | uspto-grants-2009_09 |
| ORD ID | ord-2a6c6e1e5fbe45b59a49c621ac3ab274 |
| Source note | uspto-grants-2009_09 |