Butyl iodide → Ethyl (E)-4-butoxy-3-methoxycinnamate

HRID 744107

Reaction equation

HRID 744107 reaction equation
[OH:1][C:2]1[CH:14]=[CH:13][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:4][C:3]=1[O:15][CH3:16].[CH2:17](I)[CH2:18][CH2:19][CH3:20]>>[CH2:17]([O:1][C:2]1[CH:14]=[CH:13][C:5](/[CH:6]=[CH:7]/[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:4][C:3]=1[O:15][CH3:16])[CH2:18][CH2:19][CH3:20]

Participants

3

Reactant 2

HCID 10962Butyl iodideHCID 736681Ethyl Ferulate

Product 1

HCID 86746611Ethyl (E)-4-butoxy-3-methoxycinnamateYield 83.9%

Procedure

Following a procedure similar to that described in Preparation 116, but using 6.66 g of ethyl (E)-4-hydroxy-3-methoxycinnamate and 6.62 g of butyl iodide, 7.00 g of the title compound were obtained as a solid material.

Workup

  1. customthat described in Preparation 116

Sources & evidence

ORD record
ord-76ee238b6b9943e7ae88aa388dc800f9
Source dataset
uspto-grants-1996_09
Patent number
US05559109

Linked notes

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