Oxalic Acid → Carbonate oxalate

HRID 7456

Reaction equation

HRID 7456 reaction equation
[C:1](=[O:4])([O-:3])[O-:2].[C:5]([OH:10])(=[O:9])[C:6]([OH:8])=[O:7]>C(OCC)(=O)C>[C:5]([OH:10])(=[O:9])[C:6]([OH:8])=[O:7].[C:1](=[O:2])([OH:4])[OH:3]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 19660Carbonate Ion

Product 1

HCID 88099579Carbonate oxalate

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

In 7 mL of ethyl acetate was dissolved 0.31 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=methyl=carbonate, and to the solution was added a solution of 0.10 g of oxalic acid in 1 mL of ethyl acetate, after which the resulting mixture was stirred at room temperature. The crystals precipitated were collected by filtration to obtain 0.34 g of 1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}-3-azetidinyl=methyl=carbonate oxalate.

Workup

  1. customThe crystals precipitated
  2. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-969acd0d0f2e422ba1015f8da344886c
Source dataset
uspto-grants-2006_08
Patent number
US07087594B2

Linked notes

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