Hydrochloric Acid → Ethyl 4-ethoxycarbonimidoylbenzoate hydrochloride

HRID 747666

Reaction equation

HRID 747666 reaction equation
[C:1]([C:3]1[CH:13]=[CH:12][C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[CH:5][CH:4]=1)#[N:2].[ClH:14].[CH2:15]([OH:17])[CH3:16]>O1CCOCC1>[ClH:14].[CH2:15]([O:17][C:1]([C:3]1[CH:13]=[CH:12][C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])=[CH:5][CH:4]=1)=[NH:2])[CH3:16]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 81589Ethyl 4-cyanobenzoate

Product 1

HCID 68830640Ethyl 4-ethoxycarbonimidoylbenzoate hydrochloride

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

5.16 g (29 mmol) of ethyl 4-cyanobenzoate was stirred in 50 ml of 4N solution of hydrogen chloride in dioxane. 5 ml of ethanol was added to the resultant mixture, and they were stirred at room temperature for 4 days. The solvent was evaporated, and the residue was washed with ethyl acetate and dried to obtain the title compound.

Workup

  1. customThe solvent was evaporated
  2. washthe residue was washed with ethyl acetate
  3. customdried

Sources & evidence

ORD record
ord-745c474fe6424adb93f48ea986009b47
Source dataset
uspto-grants-2008_07
Patent number
US07396844B1

Linked notes

Loading…