Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7994Generated: October 26, 2026

2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one → 4-hydroxymethyl-2-isobutyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one

https://huagongshe.com/reaction/7994

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-oneHCID 21991587—
Reactant4-carboxy-2-isobutyl-6-[4-(methylthio)phenyl)-2H-pyridazin-3-oneHCID 21991639—
Product4-hydroxymethyl-2-isobutyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 2199165035.3%

Reaction Steps

Following the procedure of Example 1 (8), 4-carboxy-2-isobutyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one was reacted to yield the title compound as a yellow oil (yield: 35.3%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-4890823ff7fb4745a8939acecea10f65
Source noteuspto-grants-2006_08