Dimethyl Sulfoxide → 5-Amino-2-fluoroisonicotinic acid

HRID 800192

Reaction equation

HRID 800192 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[c:10]([C:16](=[O:17])[OH:18])[cH:11][c:12]([F:15])[n:13][cH:14]1)([CH3:5])([CH3:6])[CH3:7].[CH3:26][S:27]([CH3:28])=[O:29].[F:19][C:20]([F:21])([F:22])[C:23]([OH:24])=[O:25]>>[NH2:8][c:9]1[c:10]([C:16](=[O:17])[OH:18])[cH:11][c:12]([F:15])[n:13][cH:14]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 6422Trifluoroacetic acidHCID 106110655-((tert-Butoxycarbonyl)amino)-2-fluoroisonicotinic acid

Product 1

HCID 27625115-Amino-2-fluoroisonicotinic acid

Sources & evidence

ORD record
ord-9e423dc4d476467a8a086114d64460e6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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