Borane → N-(5-Bromo-2-chlorobenzyl)cyclopropanamine

HRID 800971

Reaction equation

HRID 800971 reaction equation
[BH3:15].[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:14])[c:6]([C:7](=[O:8])[NH:9][CH:10]2[CH2:11][CH2:12]2)[cH:13]1.[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([Cl:14])[c:6]([CH2:7][NH:9][CH:10]2[CH2:11][CH2:12]2)[cH:13]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028TetrahydrofuranHCID 48069835-bromo-2-chloro-N-cyclopropylbenzamide

Product 1

HCID 43378984N-(5-Bromo-2-chlorobenzyl)cyclopropanamine

Sources & evidence

ORD record
ord-d6afa543857b4c79bb740b3c79ab4b2a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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