Dimethylformamide → 1-[4-(6-Amino-pyrimidin-4-ylmethyl)-phenyl]-3-(3-trifluoromethyl-phenyl)-urea
Reaction equation
[F:27][C:28]([c:29]1[cH:30][c:31]([N:35]=[C:36]=[O:37])[cH:32][cH:33][cH:34]1)([F:38])[F:39].[NH2:1][c:2]1[cH:3][c:4]([CH2:8][c:9]2[cH:10][cH:11][c:12]([NH:15][C:16]([NH:17][c:18]3[cH:19][cH:20][c:21]([CH2:22][CH3:23])[cH:24][cH:25]3)=[O:26])[cH:13][cH:14]2)[n:5][cH:6][n:7]1.[O:40]=[CH:41][N:42]([CH3:43])[CH3:44]>>[NH2:1][c:2]1[cH:3][c:4]([CH2:8][c:9]2[cH:10][cH:11][c:12]([NH:15][C:36]([NH:35][c:31]3[cH:30][c:29]([C:28]([F:27])([F:38])[F:39])[cH:34][cH:33][cH:32]3)=[O:37])[cH:13][cH:14]2)[n:5][cH:6][n:7]1Participants
4
Sources & evidence
- ORD record
- ord-5340fd262fef45fd8cfaedcd905e5c41
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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