Hydrochloric Acid → 5-Chloro-2-(piperidin-1-yl)aniline

HRID 803177

Reaction equation

HRID 803177 reaction equation
[C:21](=[O:22])([OH:23])[O-:24].[CH3:26][OH:27].[Cl:5][c:6]1[cH:7][c:8]([N+:18]([O-:19])=[O:20])[c:9]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:10][cH:11]1.[ClH:1].[Na+:25].[Sn:2]([Cl:3])[Cl:4]>>[Cl:5][c:6]1[cH:7][c:8]([NH2:18])[c:9]([N:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ionHCID 24479Stannous ChlorideHCID 2853181-(4-Chloro-2-nitrophenyl)piperidine

Product 1

HCID 2853175-Chloro-2-(piperidin-1-yl)aniline

Sources & evidence

ORD record
ord-6138b2ade97143dd9e7be13d04d8d6a5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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