Iodoethane → Ethyl(triphenylmethyl)amine

HRID 80320

Reaction equation

HRID 80320 reaction equation
[C:1]1([C:7]([NH2:20])([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.I[CH2:22][CH3:23]>C(#N)C>[C:1]1([C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:20][CH2:22][CH3:23])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 6340IodoethaneHCID 138598Tritylamine

Product 1

HCID 4447360Ethyl(triphenylmethyl)amineYield 28%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Triphenylmethylamine (1.00 g, 3.86 mmol) (Wako Pure Chemical Industries, Ltd.) and iodoethane (1.50 g, 9.62 mmol) (Wako Pure Chemical Industries, Ltd.) were dissolved in acetonitrile (5 mL) (Wako Pure Chemical Industries, Ltd.), and the mixture was left to stand still at room temperature for 3 days. The solvent was distilled off under reduced pressure, and the residue was subjected to silica gel column chromatography (chloroform (Wako Pure Chemical Industries, Ltd.) as an eluent), to thereby obtain the title compound (0.31 g, 28% yield).

Workup

  1. waitthe mixture was left
  2. distillationThe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-b13daa3783284fc5acaee76552dcdb91
Source dataset
uspto-grants-2014_09
Patent number
US08846012B2

Linked notes

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