Dichloromethane → 6-[8-(4-Morpholin-4-yl-phenylamino)-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]-3,4-dihydro-2H-isoquinolin-1-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:7]([c:8]1[c:9]2[n:10]([c:11](-[c:14]3[cH:15][c:16]4[c:21]([cH:22][cH:23]3)[C:20](=[O:24])[NH:19][CH2:18][CH2:17]4)[cH:12][n:13]1)[n:25][cH:26][n:27]2)[c:28]1[cH:29][cH:30][c:31]([N:34]2[CH2:35][CH2:36][O:37][CH2:38][CH2:39]2)[cH:32][cH:33]1)([CH3:5])([CH3:6])[CH3:40].[Cl:48][CH2:49][Cl:50].[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47]>>[NH:7]([c:8]1[c:9]2[n:10]([c:11](-[c:14]3[cH:15][c:16]4[c:21]([cH:22][cH:23]3)[C:20](=[O:24])[NH:19][CH2:18][CH2:17]4)[cH:12][n:13]1)[n:25][cH:26][n:27]2)[c:28]1[cH:29][cH:30][c:31]([N:34]2[CH2:35][CH2:36][O:37][CH2:38][CH2:39]2)[cH:32][cH:33]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-be926e826d3b4c8bbe8d7af525d7e3df